Publications

Affichage de 331 à 340 sur 5615


  • Article dans une revue

A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer's disease

S. Tsartsalis, H. Sleven, N. Fancy, F. Wessely, A. M. Smith, N. Willumsen, T. K. D. Cheung, M. J. Rokicki, V. Chau, E. Ifie, C. Khozoie, O. Ansorge, X. Yang, M. H. Jenkyns, K. Davey, A. Mcgarry, R. C. J. Muirhead, Stephanie Debette, J. S. Jackson, A. Montagne, D. R. Owen, J. S. Miners, S. Love, C. Webber, M. Z. Cader, P. M. Matthews

Brain perfusion and blood-brain barrier (BBB) integrity are reduced early in Alzheimer's disease (AD). We performed single nucleus RNA sequencing of vascular cells isolated from AD and non-diseased control brains to characterise pathological transcriptional signatures responsible for this. We…

Nature Communications, 2024, 15 (1), pp.2243. ⟨10.1038/s41467-024-46630-z⟩. ⟨hal-04654261⟩

  • Article dans une revue

Teclistamab Improves Patient-Reported Symptoms and Health-Related Quality of Life in Relapsed or Refractory Multiple Myeloma: Results From the Phase II MajesTEC-1 Study

Thomas G. Martin, Philippe Moreau, Saad Usmani, Alfred Garfall, María-Victoria Mateos, Jesús San-Miguel, Albert Oriol, Ajay Nooka, Laura Rosinol, Ajai Chari, Lionel Karlin, Amrita Krishnan, Nizar Bahlis, Rakesh Popat, Britta Besemer, Joaquín Martínez-López, Michel Delforge, Danielle Trancucci, Lixia Pei, Rachel Kobos, John Fastenau, Katharine Gries, Niels W.C.J. van de Donk

Clinical Lymphoma, Myeloma & Leukemia, 2024, 24 (3), pp.194-202. ⟨10.1016/j.clml.2023.11.001⟩. ⟨hal-04920999⟩