MustImplant

Taking into account quantitatively a vast set of data encountered in the bibliography, the concept consists in designing an optimal functional surface thanks to an original methodology based on a new knowledge management tool. This generic surface texturing approach will be applied to the texturing of endosseous implants, to enhance their performance and safety. The two academic partners' 25 years of collaboration on this project and their advanced understanding of the influence of surface topography on bone cells will enable them to design optimal topographies. After manufacturing implants with these optimal topographies using innovative Femtolaser-based manufacturing techniques, they will be tested mechanically, chemically and biologically to provide proof of concept and validate osteoconductive topographies at the end of the project.

The challenge: is it possible to design and femtolaser-texture an optimal surface topography obtained by mixing a set of existing surface topographies known for their high biological functionalities?

Many in vitro and in vivo studies have demonstrated the role of topography on bone cells but also on implant anchorage in bone tissue. However, defining the best topography to promote implant anchorage in bone tissue is still currently done empirically. Our ambition in this project is to propose a knowledge capitalization approach for intelligent texturing of medical implants.